Summary
Introduction. Despite the association between metabolic syndrome and hyper - uricaemia found in studies, the effect of specific food in take and dietary habits on blood uric acid levels is still unclear.
Aim of the study. The aim of this study is to examine the associations between uric acid and eating habits in a large group of patients with metabolic syndrome.
Material and methods. This cross-sectional study included 709 participants with previously diagnosed metabolic syndrome based on 2005 NCEP III modified criteria. All patients were separated in two groups depending on uric acid levels and sex. The blood samples were taken for biochemical evaluations of uric acid and serum total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol and triglycerides. In addition, the participants’ nutrition profile was assessed using questionnaire based on Choi et al.
Results. In different gender groups, both high-density lipoprotein cholesterol (p<0.001) and low-density lipoprotein cholesterol (p=0.035) were slightly higher in women, whereas water intake (p<0.001) was significantly higher compared to men. Male triglyceride concentrations (p<0.001), meat (p<0.001), protein (p=0.014) and alcohol (p<0.001) consumption were significantly higher. A comparison of uric acid groups showed a reduced in direct correlation with increased dairy intake (r=-0,12; p<0.001) and a higher alcohol consumption was directly associated with higher uric acid intake (r=0.16; p<0.001).
Conclusions. Based on statistical methods we conclude that dairy products, in contrast to alcohol consumption, may work beneficially on lowering serum uric acid level and has a positive effect on the control of hyperuricemia in a population of patients with metabolic syndrome.
