Imunohaematological View of Laboratory Diagnostics for Foetus Haemolytical Disease
Ramunė Šepetienė
Summary
Fast developing science of medicine, consolidates relationship among the different fields of specialists to optimize patient’s quality of care. Due to a misunderstanding how to make an appropriate decision to manage a situation, the most complicated and expensive diagnostic procedures are being involved instead of well known serological investigations which are modern developed but not enough valuable within imunohaematologists due to their shortage. There are unknown priorities for the serological laboratory yet, and all scientific comments and proposals have no response among clinicians.
Important data about prevention and laboratory diagnostics for Haemolytic Disease of Foetus for pregnant women are established in this review. There are described serological data to be realized and prioritize to update the management and rules of assays in the laboratory. This is not a review pretending to describe the alphabet of imunohaemathology or trying to attempt clinicians how to cure the HDF. As well known the advent of Rh immune globuline has decreased the incidence of D-associated HDF due successful anti-D prophylaxis but HDF caused by antigens other than D is increasing in preval ence perhaps to less known or unknown importance to develop the alloimunisation in pregnancy as the investigation of clinical important role is still in progress. The integration and involvement of the laboratory findings promotes the basic key for HDF management. It’s extremely important to organize clinical support for doctors, interpreting the results of the serological findings trying to extract the maximum capacity for the patients. The molecular investigations are becoming more popular and visible for each section, immunohaematology tests to be referable to complete diagnostics to obtain appropriate results in any discrepancies. This article is rehabilitation for serological investigations, the importance for the HDF laboratory diagnostics.
Keywords: immunohaematology, RBC alloimunisation, alloantibodies, laboratory tests for pregnant, haemolytic disease of foetus.
