In Vitro Fertilization: It's Success Rate's Dependency on Age, Body Mass Index, and the Concentration of Anti-Mullerian Hormone Before Procedure

You are here

Laboratorinė medicina. 2017,
t. 19,
Nr. 4,
p. 224 -
227

Objective. The aim of the study was to analyse whether age, Body Mass Index (BMI) and Anti-Mullerian hormone (AMH) have an effect on pregnancy rate after performing in vitro Fertilisation (IVF) and Intracytoplasmic Sperm Infection (ICSI) procedures.

Research and methods. A retrospective study of 1166 stimulated cycles had been carried out at the “Vaisingumo klinika”. The women were examined according to their age, BMI, and AMH before the procedure.

Results. 40.05% of women became pregnant after IVF/ICSI procedures. It was determined that the age and BMI corellate with pregnancy rate statistically significantly after IVF and ICSI procedures (p=0.001 and p=0.0001), while the level of AMH does not correlate with anything (p=0.264). The group divided accordjng to their BMI consisted mostly of women having adequate weight. The second group of women divided according to their AMH level in the blood serum mostly had a normal AMH level, while only a small part of women had a high level of AMH. The study consisted mostly of women who were younger than 35 years and only a small part of women were older than 40 years old. The best results after IVF/ICSI procedures were seen in women with normal weight (45.13%), normal AMH (42.55%), and up to 35 years of age (44.71%). The lowest birth rate was found in the obese women’s group (8.42%), with a low AMH (28.57%), and over 40 years of age (17.02%).

Conclusions. Age and BMI have a statistically significant correlation with pregnancy rate after IVF and ICSI procedures, while the level of AMH does not affect the outcome of these procedures.

© 2024, Lithuanian Society of Laboratory Medicine