Background. Although importance of genetic factors in epilepsy is undisputable, genetic structure of epilepsies is largely unknown. Knowledge of etiological structure of monogenic diseases associated with epilepsy or seizures may aid in the choice of proper genetic testing methods and algorithms. Besides, it may enable further studies into etiopathophysiological studies of ictogenesis and epileptogenesis.
Objective. To evaluate the clinical manifestation and its frequency in children with tuberous sclerosis complex and to compare with literature data.
Material and methods. A retrospective data analysis of children with clinically or genetically diagnosed Tuberous sclerosis complex in Vilnius University Santariskiu Clinics Children Hospital.
