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Summary

Introduction. Vitreoretinal lymphoma is the most common intraocular lymphoma, with a steadily increasing incidence. Its clinical resemblance to uveitis makes diagnosis challenging, and the prognosis remains poor. Despite treatment, progression to the central nervous system is common, with a five-year mortality rate of up to 90%. However, early diagnosis can delay progression and improve quality of life.

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Acute lymphoblastic leukemia is a malignant proliferation of lymphoid cells blocked at an early stage of difterentiation. It emerges after a consecutive mutations in genes important for blood cell development. Acute lymphoblastic leukemia is the most common malignancy among children. The incidence in Lithuania is 3.2-3.6 cases per 100 000 children a year. Almost 90 percent of aftected children are cured using contemporary treatment protocols, although chemotherapy caused complications can have a deleterious effect on quality of life.

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