Frederikson’s classification of dyslipoproteinemias is based on clinical features and electrophoretic or ultracentrifugal pattern of lipoprotein fractions. It was recognized as the international standard of dyslipoproteinemia classification in 1972 by the World Health Organization. Type I dyslipoproteinemia is represented by three rare genetic disorders, i.e., familial lipoprotein lipase deficiency, familial apolipoprotein C-II deficiency and lipoprotein lipase deficiency due to familial inhibitor of lipoprotein lipase, which are inherited in autosomal recessive pattern.
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