antikoaguliantai

Introduction. Vitamin K antagonist warfarin or the new oral anticoagulants (NOAC), a direct thrombin or factor Xa inhibitors, are increasingly prescribed for long-term prophylaxis of thrombotic complications. It is recognized that it is still difficult to evaluate the specific effects of NOAC’s on the clotting system by laboratory tests. There is also the lack of antidotes for rapid reversion of NOAC.