Summary
Background. The study evaluates the current landscape of laboratory diagnostics for bleeding disorders across the Baltic countries, where outdated guidelines (2009–2010) hinder diagnostic accuracy and standardization.
Methods. An initiative Baltic working group for bleeding disorders developed a questionnaire to assess the operational status and diagnostic capabilities of laboratories in Lithuania, Latvia, and Estonia. This survey covered 48 laboratories, of which 36 responses were analyzed.
Results. Results indicate considerable variability in laboratory capabilities, accreditation status, and available diagnostic assays, with only half of the laboratories accredited under ISO 15189. Most laboratories employ basic screening tests like PT/INR, aPTT, and fibrinogen; however, advanced assays and specialized diagnostics for conditions such as von Willebrand disease and haemophilia are limited. The findings reveal geographic and institutional disparities in methodologies (e. g., Quick vs. Owren method for PT), reflexive testing practices, and clinical algorithm implementation. Participation in EUHANET remains low, with few institutions recognized as comprehensive or treatment centers, signaling limited access to specialized networks.
Conclusions. To mitigate these gaps, updated guidelines tailored to the capabilities of laboratories across the Baltic region are recommended. These guidelines should align with international standards to enhance diagnostic quality and ensure equitable patient care.
