Early and long-term increase of traditional markers of atherosclerosis are the main risk factors of this disease and its complications, in other hand they all ow you to measure, monitor and predict the course of the disease. This paper describes the most important traditional atherosclerosis risk factors, their importance in the pathogenesis of atherosclerosis and presented biochemical phenotype results of Lithuanian project.
In April of 2011 a large-scale population study of Lithuania - LITGEN project, was started. Within this proj ect in relatively healthy individuals of different eth- nolinguistic regions various biochemical parameters were investigated: serum total cholesterol, high density lipoprotein cholesterol, low-density lipoprotein cholesterol, triacylglycerol, glucose, C-reactive protein, ApoAl, ApoB, ApoB / Apo A1 ratio and lipoprotein (a).
Totally we investigated 1349 individuals: 605 men and 737 women. In women group, even in early age (0-17 years) 24% of the total cholesterol results exceed the recommended limits. Under strict American Heart Association guidelines the results of total chol esterol of 54% women and 34% of men and results of LDL cholesterol of 35% women and 21.5% of men would be above these limits. Traditional atherosclerosis markers results which ex ceed rec ommended lim its in crease with age. In both men and women older than 65 years group hsCRB results are significantly higher than in all other age groups.
Keywords: atherosclerosis, cholesterol, ApoAI, ApoB, Lp(a).
