Seasonality of Serum 25-Hydroxy-Vitamin D Levels and Associations with Anthropometrical and Laboratory Parameters

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Laboratorinė medicina. 2013,
t. 15,
Nr. 4,
p. 188 -
193

Study aim. To investigate seasonal changes in levels of serum 25-hydroxy-vi- tamin D (25OH-D) - the marker of vita­min D status - and its associations with several routine clinical parameters in young men.

Materials and Methods. Randomly selected generally healthy men of age 20-39 were examined during February or March (cold season) and re-examined in August or September (warm season). Some anthropometrical (height, weight, waist and hip circumference, arterial blood pressure) and laboratory measure­ments (lipids, high sensitivity CRP, glu­cose, 25OH-D) were performed.

Results. During 2012 and 2013, in total 130 men were included and 125 of them were re-examined. At cold season 96.93% were vitamin D deficient or insuf­ficient, at warm season 46.80% had low vitamin D. At warm season, normally weighted men had higher 25OH-D levels comparing with obese or overweight men; in addition, 25OH-D negatively corre­lated with glucose and triglycerides lev­els.

Conclusions. Low vitamin D status in young generally healthy men appears to be a quite common probiem both in cold and in warm seasons. Inverse 25OH-D associations with body mass in­dex, glucose and triglycerides were de­tected.

Keywords: vitamin D, calcidiol, seasons, men, body mass index.

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