The Role Of Laboratory Analysis In Diagnostics Of Ocular Toxoplasmosis: A Case Report

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Laboratorinė medicina. 2015,
t. 17,
Nr. 2,
p. 72 -
76

Background. Toxoplasmosis - one of the most common zoonosis, infecting more than one third of world population. Ocular toxoplasmosis generally causes posterior uveitis, resulting in blurred vision. Infection is usually asymptomatic. Central chorioretinitis - the commonest form of ocular toxoplasmosis. Clinical view, serological and aqueous humor laboratory analysis let us diagnose ocular toxoplasmosis.

Clinical presentation. 27 years old patient noticed a mist over his left eye in 2010. Panuveitis, vitritis, chorioretinitis acuta oculus sinistra was diagnosed. Results of specific serological analysis after infectionist consultation: anti-toxo IgG positive -64.2, anti-toxo IgM - negative. Several old and one new chorioretinal scars were found while fundus ophtalmoscopy. Patient was treated with parabulbaric injections of Sol. Dexamethasoni, Sol. DexaChlora, Sol. Uniclopheni and specific systemic antitoxoplasmic medications: Tab. Pyrimethamini, Tab. Sulfadiazini, Tab. Acidum folicum. A new scar became localized, non-oedematous after 1.5 month of treatment. Prophylactic treatment with Tab. Pyrimethamini for 3 months was admini stered. The mist over the patient's left eye recrudesced in 2014. In fundus: area of chorioretinal oedema. Anti-toxo IgG - 8.3. Patient was repeatedly treated with Sol. Dexamethasoni parabulbaric injections, Sol. Nepafenac, Tab. Pyrimethamini. The chorioretinal oedema has reduced. Prophylactic treatment has been proceeded.

Conclusions. Toxoplasmosis - a worldwide prevalent infection disease, often led by recurring chorioretinitis as its most common form. Anamnesis, eye fundus examination and laboratory analysis - the most important diagnostic aspects of ocular toxoplasmosis. There is lack of disease diagnostic tests using aqueous humor in Lithuania.

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