structural changes of X chromosome

Background. The purpose of this study was to perform analysis of X chromosome monosomy and structural changes detected during routine karyotyping in The Center for Medical Genetics of Vilnius University Hospital “Santariskiu Klini­kos” (CMG VUHSK) from 1999 to 2015, and to evaluate the age of patients at the time of diagnosis. Additionally, the review of the recommendations for management of patients with Turner syndrome was performed.