Among end-stage renal disease patients, the risk of cardiovascular moribidity and total mortality is significantly higher than in healthy individuals. As interventions that have been successful in the general population, failed to improve outcomes of hemodialysis patients, more attention is paid to non-traditional, only for hemodialysis patients specific risk factors. Disturbances of calcium phosphate metabolism and related vascular calcification is one of them. Vascular calcification is not any longer considered a passive process, but rather as an actively regulated one.
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