Summary
Introduction. Glioblastoma, accounting for 48.6% of primary malignant brain tumours, is the most aggressive form, severely impairing the quality of life of patients and caregivers due to neurological, cognitive, and emotional symptoms. Fear of death, physical decline, and disease burden prompt the search for effective coping strategies.
Aim. This study analyses coping strategies used by glioblastoma patients and their caregivers and their impact on managing disease-related challenges.
Methods. A literature review was conducted using PubMed with keywords: “coping,” “coping strategies,” “coping mechanisms,” “coping style,” “glioblastoma,” “high-grade glioma,” and “glioma.” Eight articles focusing on coping strategies of glioblastoma patients and caregivers were reviewed.
Results. Coping strategies change over time. Early stages often involve fighting and avoidance, while recurrence sees fatalism and helplessness. Problem-solving and positive thinking improved caregivers’ quality of life but had limited effects on patients. Avoidance strategies showed situational benefits for patients, enhancing some quality-of-life metrics but negatively affected caregivers. Spiritual well-being, offering meaning and calm, reduced stress, increased resilience, and improved quality of life and survival rates.
Conclusions. Coping strategies in glioblastoma evolve and impact patients and caregivers differently. Spiritual well-being plays a crucial role in enhancing emotional resilience and quality of life.

